TY  - JOUR
AU  - Yurakate, Natthika
AU  - Phanasathit, Muthita
PY  - 2022/08/29
Y2  - 2026/03/01
TI  - Mortality Rate and Associated Factors in Critically Ill  Intubated Patients with Coronavirus Disease 2019  (COVID-19) at Pranangklao Hospital
JF  - Asian Medical Journal and Alternative Medicine
JA  - AMJAM
VL  - 22
IS  - 2
SE  - Original Articles
DO  - 
UR  - https://asianmedjam.com/index.php/amjam/article/view/316
SP  - 127-137
AB  - &lt;p&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; In the epidemic wave of the ongoing coronavirus disease 2019 (COVID-19) pandemic in April 2021. This study aimed to explore the 30-day mortality rate and its associated factors and anesthetic practice in critically ill COVID-19 patients who received intubation.&lt;br /&gt;&lt;strong&gt;Methods:&lt;/strong&gt; This retrospective cohort study was collected data from medical records in critically ill COVID-19 patients who received intubation and admitted to Pranangklao Hospital (PNKH) from April 1 to June 30, 2021. &lt;br /&gt;&lt;strong&gt;Results:&lt;/strong&gt; A total of 73 patients were admitted and intubated with the median age was 65 years (IQR = 18), 43 (58.9%) were male, 37 (50.7%) were body mass index (BMI) ≥ 30 kg/m&lt;sup&gt;2&lt;/sup&gt;, and 60 (82.2%) had underlying diseases. The most common underlying diseases were hypertension (63.00%) and diabetes (47.90%). The 30-day mortality rate was 79.50%. Compared between the survivors (n = 15) and non-survivors (n = 58), the mortality significantly increased with age (&lt;em&gt;P&lt;/em&gt; = .002), more underlying diseases (&lt;em&gt;P&lt;/em&gt; = .007), having cough (RR&lt;sub&gt;adj&lt;/sub&gt; 31.90, 95% CI = 1.67-610.65, &lt;em&gt;P&lt;/em&gt; = .021), and more complications (RR&lt;sub&gt;adj&lt;/sub&gt; 2.58, 95% CI = 1.02-6.51, &lt;em&gt;P&lt;/em&gt; = .045). The anesthetics were used as follows: midazolam (80.95%), thiopental (40.48%), propofol (26.19%), and ketamine (23.81%). The muscle relaxants used in intubation included succinylcholine (90.48%) and rocuronium (9.52%).&lt;br /&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; Critically ill intubated COVID-19 patients showed a very high mortality rate that significantly increased with age, underlying diseases, and complications. Intubation treatment in vulnerable populations should be done cautiously to avoid adverse events.&lt;/p&gt;
ER  -