TY - JOUR AU - Traitanon, Opas AU - Boongerd, Thanarak AU - Dumnin, Songphon AU - Buekban, Chatchai AU - Pongthornseri, Ronachai AU - Sampnyuth, Supat AU - Thanawattano, Chusak AU - Surangsrirat, Decho PY - 2021/08/27 Y2 - 2026/03/01 TI - An Initial Report on Operability and Safety of A Domestic Automated Peritoneal Dialysis Machine in Thailand JF - Asian Medical Journal and Alternative Medicine JA - AMJAM VL - 21 IS - 2 SE - Original Articles DO - UR - https://asianmedjam.com/index.php/amjam/article/view/264 SP - 91-96 AB - <p><strong>Background:</strong> Thailand had implemented the peritoneal dialysis first (PD first) policy which allowed access to peritoneal dialysis as a first-line treatment for end-stage renal disease (ESRD). However, all the patients under this policy are allowed to use only the self-operated Continuous Ambulatory Peritoneal Dialysis (CAPD) but not the Automated Peritoneal Dialysis (APD). While APD has a lot of advantages over CAPD, its cost is more than double in Thailand. Under these circumstances, it is crucial to produce APD equipment with a trade-off between good performance and affordable price.</p><p><strong>Methods:</strong> This study is a pilot cross-sectional study to evaluate the operability and safety of the domestically developed APD machine. Three stable ESRD patients already treated with APD machines were recruited for the 7-day trial.</p><p><strong>Results:</strong> There is a slight decrease in the dwell time due to the longer operational time of the developed machine; 11.26 ± 2.29%. Increases in serum creatinine and blood urea nitrogen were observed; 3.01 ± 1.83% and 22.92 ± 4.48%, respectively. No major adverse events were reported.</p><p><strong>Conclusion:</strong> The developed machine used only gravity for the exchange, the dwell time was decreased as expected, resulting in a lower exchange of the waste products from the blood to the peritoneal cavity. Even though the results show a slightly lower treatment performance, no clinical significance during short-term follow-up was observed. To obtain similar performance for the domestically developed APD machine, total treatment time could be increased to maintain comparable dwell time overnight.</p> ER -