@article{Yurakate_Phanasathit_2022, title={Mortality Rate and Associated Factors in Critically Ill Intubated Patients with Coronavirus Disease 2019 (COVID-19) at Pranangklao Hospital}, volume={22}, url={https://asianmedjam.com/index.php/amjam/article/view/316}, abstractNote={<p><strong>Introduction:</strong> In the epidemic wave of the ongoing coronavirus disease 2019 (COVID-19) pandemic in April 2021. This study aimed to explore the 30-day mortality rate and its associated factors and anesthetic practice in critically ill COVID-19 patients who received intubation.<br /><strong>Methods:</strong> This retrospective cohort study was collected data from medical records in critically ill COVID-19 patients who received intubation and admitted to Pranangklao Hospital (PNKH) from April 1 to June 30, 2021. <br /><strong>Results:</strong> A total of 73 patients were admitted and intubated with the median age was 65 years (IQR = 18), 43 (58.9%) were male, 37 (50.7%) were body mass index (BMI) ≥ 30 kg/m<sup>2</sup>, and 60 (82.2%) had underlying diseases. The most common underlying diseases were hypertension (63.00%) and diabetes (47.90%). The 30-day mortality rate was 79.50%. Compared between the survivors (n = 15) and non-survivors (n = 58), the mortality significantly increased with age (<em>P</em> = .002), more underlying diseases (<em>P</em> = .007), having cough (RR<sub>adj</sub> 31.90, 95% CI = 1.67-610.65, <em>P</em> = .021), and more complications (RR<sub>adj</sub> 2.58, 95% CI = 1.02-6.51, <em>P</em> = .045). The anesthetics were used as follows: midazolam (80.95%), thiopental (40.48%), propofol (26.19%), and ketamine (23.81%). The muscle relaxants used in intubation included succinylcholine (90.48%) and rocuronium (9.52%).<br /><strong>Conclusions:</strong> Critically ill intubated COVID-19 patients showed a very high mortality rate that significantly increased with age, underlying diseases, and complications. Intubation treatment in vulnerable populations should be done cautiously to avoid adverse events.</p>}, number={2}, journal={Asian Medical Journal and Alternative Medicine}, author={Yurakate, Natthika and Phanasathit, Muthita}, year={2022}, month={Aug.}, pages={127–137} }