@article{Chintanavilas_Methachittiphan_Apiyasawat_2023, title={Usage of Shanghai Scoring System for Predicting Ventricular Arrhythmic Events in Brugada Syndrome (BrS) Patients in Thailand}, volume={23}, url={https://asianmedjam.com/index.php/amjam/article/view/1435}, abstractNote={<p><strong>Background</strong>: Many risk factors are associated with ventricular arrhythmic events in Brugada syndrome <strong>(</strong>BrS<strong>)</strong> patients<strong>. </strong>The Shanghai scoring system for diagnosis of BrS was initially published in 2015<strong>.</strong><sup>1</sup> A single study also validated using this scoring system for risk stratification of arrhythmic events in BrS patients<strong>.</strong><sup>2</sup> There has been no study to demonstrate the role of this scoring system in the risk stratification of BrS patients in the Thai population<strong>. </strong>This study aimed to evaluate the role of the Shanghai scoring system in predicting ventricular arrhythmic events in Thai BrS patients<strong>.</strong></p> <p><strong>Method</strong>: We studied a retrospective cohort of BrS patients who were diagnosed from 1999 to 2019 at Ramathibodi Hospital<strong>. </strong>The patients were classified according to the Shanghai scoring system<strong>. </strong>All patients were followed for arrhythmic events and clinical outcomes<strong>. </strong></p> <p><strong>Result</strong>: 54 Patients <strong>(</strong>14 with cardiac arrest, 30 with syncope, 3 agonal respirations, and 7 asymptomatic<strong>) </strong>were classified by the Shanghai score into group A (Very high risk); score <strong>≥ </strong>5<strong>.</strong>5 <strong>(</strong>n<strong>=</strong>34<strong>)</strong>, group B (High risk); score 4<strong>-</strong>5 <strong>(</strong>n<strong>=</strong>14<strong>) </strong>and group C (Non-high risk); score <strong>≤</strong> 3<strong>.</strong>5 <strong>(</strong>n<strong>=</strong>6<strong>). </strong>During the follow<strong>-</strong>up period of 114 months, 11 arrhythmic events occurred<strong> (</strong>1 sudden cardiac arrest, 9 appropriate ICD therapy, 1 documented VT<strong>/</strong>VF from surface ECG<strong>). </strong>Incidence of ventricular arrhythmic events was highest in Group A<strong> (</strong>26<strong>.</strong>5<strong>%)</strong>, followed by Group B<strong> (</strong>14<strong>.</strong>3<strong>%)</strong>, and no event in Group C<strong>. </strong>Shanghai scores of more than 3<strong>.</strong>5 tend to be associated with increased ventricular arrhythmic events <strong>(</strong>HR 4<strong>.</strong>85, CI 0<strong>.</strong>037<strong>-</strong>630<strong>.</strong>2, p<strong>=</strong>0<strong>.</strong>525<strong>)</strong>, compared to the lower risk group<strong> (</strong>Shanghai score <strong>≤ </strong>3<strong>.</strong>5<strong>). </strong>Five inappropriate ICD shocks occurred<strong>. </strong>Device<strong>-</strong>related complications occurred in 8 patients, with lead fracture being the most frequent complication<strong> (</strong>9<strong>.</strong>3<strong>%). </strong></p> <p><strong>Conclusion:</strong> Risk stratification by the Shanghai scoring system may be useful in predicting ventricular arrhythmic events in Thai BrS patients<strong>. </strong>However, a larger cohort is needed for statistically significant results<strong>.</strong></p>}, number={Supplemental}, journal={Asian Medical Journal and Alternative Medicine}, author={Chintanavilas, Kumpol and Methachittiphan, Nilubon and Apiyasawat, Sirin}, year={2023}, month={Nov.}, pages={S20-S29} }