@article{Jaicharoensub_Sakpakdeecharoen_Panthong,_Itharat_2022, title={Biological Activities of Ya-Mor-Noi Remedy for Postpartum Care}, volume={22}, url={https://asianmedjam.com/index.php/amjam/article/view/1323}, abstractNote={<p><strong>Introduction:</strong> Ya-Mor-Noi (YMN) is a Thai herbal remedy used at Dansai Crown Prince Hospital, Loei Province. It consists of seven plants, including the rhizome of <em>Smilax corbularia</em> (SC), the stem of <em>Caesalpinia sappan</em> (CS), <em>Goniothalamus laoticus</em> (GL), <em>Polyalthia suberosa</em> (PS), <em>Glycosmis pentaphylla</em> (GP), <em>Croton persimili</em>s (CP), and <em>Diospyros ehretioides</em> (DE). For over 20 years, YMN has been prescribed for patients admitted to post-partum wards after delivery to efficiently reduce inflammation and rehabilitate them.</p> <p><strong>Objectives:</strong> To study biological activities of YMN extracts relating to postpartum conditions, including anti-inflammatory, wound healing activities and investigating its main compound.</p> <p><strong>Methods:</strong> Extraction methods comprised maceration at 95%, ethanol at 50%, and decoction. Anti-inflammatory activity was investigated by determining the production of nitric oxide (NO) from RAW264.7 cells. Wound healing activity was investigated by scratch assay and the main compounds investigating through high-performance liquid chromatography (HPLC).</p> <p><strong>Results:</strong> Ethanolic extracts of YMN showed inhibition of nitric production. The decoction extract showed significant difference in wound recovery compared to the control. HPLC fingerprint analysis indicated two main compounds: Brazilin and Astilbin.</p> <p><strong>Conclusions:</strong> It is concluded that YMN produced anti-inflammatory and increased percentage of wound recovery. These findings support usage of YMN to treat postpartum patients by traditional medicine practitioners in Thailand.</p>}, number={-}, journal={Asian Medical Journal and Alternative Medicine}, author={Jaicharoensub, Jaiboonya and Sakpakdeecharoen, Intouch and Panthong, Sumalee and Itharat, Arunporn}, year={2022}, month={Aug.}, pages={S106} }